The Institute of Bio-Architecture and Bio-Interactions (IBABI) is dedicated to integrating structural biology, systems biology, computational science, and artificial intelligence to elucidate the intricate architecture and dynamic interactions of living systems across multiple scales, from atoms and molecules to cells and biological networks. The institute aims to uncover the fundamental principles governing biological organization, regulation, and function, providing a structural and mechanistic foundation for innovation in life sciences and medicine.
IBABI's research spans a broad spectrum, including the structural and functional analysis of biomacromolecules, host–pathogen interactions, molecular mechanisms of antibiotic resistance, physicochemical bases of phase separation, immune receptor recognition and signaling regulation, as well as AI-driven protein design and drug discovery. Leveraging cutting-edge technologies such as cryo-electron microscopy (cryo-EM), single-molecule imaging, computational modeling, and machine learning, IBABI drives innovation from molecular discovery to translational applications.